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Table 11 Incremental cost-effectiveness ratio of HPV vaccination alone compared to cervical cancer screening alone: Incremental cost-effectiveness ratio of HPV vaccination and cervical cancer screening with applying economies of scale

From: Incorporating economies of scale in the cost estimation in economic evaluation of PCV and HPV vaccination programmes in the Philippines: a game changer?

ICER (USD/QALY)

Percent coverage of screening (with EoS approach)

Percent coverage of HPV vaccine (with EoS approach)

% coverage

10

20

30

40

50

60

70

80

90

100

10

− 310a

− 11450a

− 2230a

− 2620a

− 2760a

− 1960a

− 2150a

− 1640a

− 1790a

− 1910a

20

− 810a

760b

1530b

− 11420a

− 5400a

− 2810a

− 2870a

− 1960a

− 2130a

− 2230a

30

− 1140a

− 520a

− 840a

590b

5880c

− 12850a

− 5170a

− 2330a

− 2510a

− 2600a

40

− 1450a

− 1110a

− 1420a

− 940a

− 160a

− 750a

1480b

1350b

− 3400a

− 3150a

50

− 1750a

− 1540a

− 1840a

− 1600a

− 1290a

− 1830a

− 1470a

− 2640a

− 2450a

− 1840a

60

− 2050a

− 1920a

− 2190a

− 2070a

− 1910a

− 2370a

− 2250a

− 3010a

− 3020a

− 3050a

70

− 2350a

− 2270a

− 2530a

− 2460a

− 2390a

− 2780a

− 2750a

− 3320a

− 3380a

− 3450a

80

− 2650a

− 2610a

− 2850a

− 2820a

− 2800a

− 3150a

− 3160a

− 3630a

− 3700a

− 3790a

90

− 2950a

− 2930a

− 3160a

− 3170a

− 3170a

− 3490a

− 3530a

− 3930a

− 4020a

− 4110a

100

− 3250a

− 3250a

− 3470a

− 3500a

− 3520a

− 3820a

− 3870a

− 4230a

− 4320a

− 4420a

  1. ICER incremental cost-effectiveness ratio, EoS economies of scale, HPV human papillomavirus vaccine
  2. aCost-effective
  3. bCost-ineffective
  4. cHighly cost-ineffective