Skip to main content

Table 3 One way sensitivity analysis

From: Lifetime cost-effectiveness analysis of intraoperative radiation therapy versus external beam radiation therapy for early stage breast cancer

Variable Value used in the Markov model Value at which IORT no longer has the highest NMB
Utility QoL with no recurrence of breast cancer based on a scale of 0–1; with “1” being in perfect health and “0” resulting in death (Fig. 4) 0.92 [19] 0
Probability of recurrent cancer and death IORT (includes local and other cancer and death) > 10 years out (Fig. 5) 23% [2] > 30%
Probability of recurrent cancer and death EBRT (includes local and other cancer and death) > 10 years out (Fig. 6) 25.4% [2] < 19%
Life expectancy metastatic recurrent cancer (Fig. 7) 5.625 year and 95% CI of 5.43–5.82 [23, 24] > 51 years
Probability IORT complication long term (> 10 years) due to radiation exposure. Includes ischemic heart disease and cancers (Fig. 8) 0.31% [7] > 24%