Cost-effectiveness analysis of a universal mass vaccination program with a PHiD-CV 2+1 schedule in Malaysia

Table 1 Country-specific model parameters for Malaysia

Parameter	Value in children aged <5 y	References	Range^a	PSA distribution
Birth cohort size (2012)	508,774	[21]	Not varied	NA
Hospitalized pneumococcal meningitis
Incidence (per 100,000)^b	34.7	[25]	±50%	Triangular
CFR (%)^b	12.5–19.2	[26]	±20%	Triangular
Hospitalized pneumococcal bacteremia
Incidence (per 100,000)^b	46.3	[25]	±50%	Triangular
CFR (%)^b	4.1–4.9	[26]	±20%	Triangular
All-cause pneumonia
GP consultation rate (per 100,000)^c	4600–12,517	[25, 26]	±50%	Triangular
Hospitalization rate (per 100,000)^c	765.8	[25]	±20%	Triangular
CFR (%)^c	0.0–0.4	[26]	±20%	Triangular
All-cause AOM
GP consultation rate (per 100,000)^d	11,745–16,412	[27]	±50%	Triangular
Myringotomy procedures (per 100,000)^d	10.8–27.2	[26, 27]	±20%	Triangular

AOM acute otitis media, CFR case fatality ratio, GP general practitioner, PSA probabilistic sensitivity analysis, NA not applicable
^aRanges used in the one-way sensitivity analyses
^bAge-specific values are in Additional file 2: Table S1
^cAge-specific values are in Additional file 2: Table S2
^dAge-specific values are in Additional file 2: Table S3

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