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Table 2 Input Data: Healthcare Resource Use (HCRU) and Costs in the UK

From: A health economic model for evaluating a vaccine for the prevention of herpes zoster and post-herpetic neuralgia in the UK

 

HZ

PHN

GP visits monthly costs

Gauthier 2008 [11]

   No pain

£18.98

-

   Mild pain

£43.66

£26.18

   Moderate pain

£54.49

£26.91

   Severe pain

£64.60

£25.72

Specialist visits monthly costs

Gauthier 2008 [11]

   No pain

£4.03

-

   Mild pain

£4.53

£0.81

   Moderate pain

£6.24

£2.04

   Severe pain

£6.89

£2.81

Medication monthly costs

Gauthier 2008 [11]

   No pain

£37.14

-

   Mild pain

£43.37

£10.02

   Moderate pain

£46.17

£14.06

   Severe pain

£53.40

£23.06

Hospitalisation costs

  

Hospitalisation rate (painful cases only)

Edmunds 2001 [12]

   Age 50 - 54

0.70%

   Age 55 - 59

0.80%

   Age 60 - 64

1.10%

   Age 65 - 69

1.70%

   Age 70 - 74

2.30%

   Age 75 - 79

3.00%

   Age 80 - 84

5.20%

   Age 85+

5.90%

Length of hospital stay

Hospital Episode Statistics 2004-2005 [17]

   Duration in days

9.9

11.2

Unit Costs

NHS Reference costs 2005-2006 [18]

   Daily cost of inpatient stay

£117.00

Productivity Costs

  

Days off work

Assumption

   No Pain

8.8

-

   Mild Pain

9.6

8.8

   Moderate Pain

12.3

31.5

   Severe Pain

21.0

70.5

Unit cost

ASHE 2005 [20] (Assuming 7.5 hour work day)

   Cost per day lost

£93.75

Vaccination costs

  

Unit cost

Assumption

   One dose of vaccine

£95.00

Administration cost

PSSRU 2005 [22]/Assumption

   50% GP - 50% Nurse

£10.40