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Table 2 Average Cost per DALY in relation to the null of interventions to reduce Colorectal Cancer in selected WHO subregions

From: Prevention, screening and treatment of colorectal cancer: a global and regional generalized cost effectiveness analysis

 

AFRE

AMRA

EURC

Intervention

COST

DALYS saved

COST

per

DALY

COST

DALYS

saved

COST

per

DALY

COST

DALYS

saved

COST

per

DALY

 

I$ (mill)

 

I$

I$ (mill)

 

I$

I$ (mill)

 

I$

Current Scenario (a)

116

27,546

4,206

64,937

14,135,241

4,594

4,677

1,801,461

2,596

FOB1

4,193

98,525

42,557

11,745

1,603,126

7,326

5,440

548,649

9,915

FOB2

2,222

66,502

33,410

6,448

1,082,872

5,954

2,954

370,055

7,984

SIG5

1,407

90,077

15,620

6,807

1,463,474

4,651

2,716

492,378

5,516

COL10

1,561

117,977

13,231

7,858

2,020,645

3,889

3,070

661,542

4,641

FOB1SIG5

4,915

121,374

40,491

15,989

1,969,383

8,119

7,069

665,773

10,617

FOB50

380

12,222

31,055

1,082

198,064

5,465

526

59,843

8,786

SIG50

531

41,910

12,669

2,446

679,950

3,597

984

205,514

4,786

COL50

1,040

91,092

11,415

5,027

1,491,646

3,370

1,980

449,523

4,404

FOBSIG50

478

46,981

10,183

3,032

762,325

3,977

860

230,391

3,734

RX

1,394

837,066

1,666

73,225

14,991,673

4,884

12,145

4,200,308

2,891

FOB1RX

5,461

912,458

5,984

77,579

16,300,533

4,759

16,481

4,630,614

3,559

FOB2RX

3,524

890,163

3,959

74,346

15,929,042

4,667

14,328

4,507,099

3,179

SIG5RX

2,706

896,387

3,019

75,839

15,864,896

4,780

14,100

4,518,157

3,121

COL10RX

2,844

909,822

3,126

76,031

16,131,444

4,713

14,301

4,604,861

3,106

FOB1SIG5RX

5,110

922,577

5,539

74,917

16,382,245

4,573

15,584

4,672,483

3,335

FOB50RX

1,758

850,239

2,067

74,130

15,200,680

4,877

12,633

4,275,966

2,954

SIG50RX

1,897

867,915

2,185

74,793

15,433,538

4,846

12,975

4,357,438

2,978

COL50RX

2,377

899,415

2,643

76,236

15,881,346

4,800

13,780

4,509,360

3,056

FOBSIG50RX

2,188

871,888

2,509

75,660

15,494,325

4,883

14,712

4,377,287

3,361

FVCAMP

275

7,618

36,074

366

84,085

4,354

360

17,804

20,222

FVCAMPRX

1,681

842,102

1,996

73,476

15,037,102

4,886

12,513

4,210,885

2,972

DRE1

818

9,438

86,676

2,370

153,861

15,401

1,008

52,939

19,038

DRE1RX

2,421

846,382

2,861

75,207

15,145,147

4,966

13,299

4,259,810

3,122

Cost-effective threshold

  

4,728

  

94,431

  

20,748

Very cost-effective threshold

  

1,576

  

31,477

  

6,916

  1. (Discounted at 3% per annum & Age-Weighted).
  2. Note: Interventions that fall on expansion path are in bold type.
  3. (a) The current scenario represents the interventions which are currently being provided in the sub-regions. This differs from the reference strategy, the null, where no intervention or treatment is provided.