Short-term (at end of 12-months) | NRT + counselling | NRT + counselling + genetic test | Difference | Â |
---|---|---|---|---|
Cost for 1000 persons in each arm | $802,100 | $1,158,000 | $355,600 | Â |
Number of quitters @ 12 months | 60 | 110 | 50 | Â |
ICER - per quitter @ 12 months | - | - | $7,112 | Â |
Long-term (at end of 35 years) | Â | Â | Â | Â |
Mean cost per person | $6,600 | $6,900 | $300 | Â |
QALYs gained per person | 14.288 | 14.298 | 0.0109 | Â |
ICER - QALYs gained per person | - | - | $27,5721 | Â |
Monte Carlo simulated ICERs | Incremental costs2 | Incremental QALYs | ICERs (QALYs) | (95% CIs) |
Base case ICER | $299.46 | 0.0109 | $34,6873 | ($12,483, $87,734) |
Initial cohort aged 30 years | $341.69 | 0.0032 | $133,409 | ($53,502, $361,376) |
Initial cohort aged 60 years | $275.66 | 0.0126 | $27,601 | ($8,783, $73,948) |
Men only (aged 50 years) | $286.23 | 0.0130 | $27,182 | ($9,200, $70,783) |
Women only (aged 50 years) | $334.53 | 0.0049 | $46,408 | ($17,199, $118,383) |