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Table 7 Sensitivity analysis

From: Cost-utility of Intravenous Immunoglobulin (IVIG) compared with corticosteroids for the treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Canada

Parameter varied Incremental Costs (IVIG-corticosteroids) Incremental QALYs (IVIG-corticosteroids $/QALY IVIG vs. corticosteroids
Patient Weight    
35 kg $58,102 0.177 $327,665
45 kg $74,043 0.177 $417,569
55 kg $89,985 0.177 $507,474
65 kg $105,927 0.177 $597,378
75 kg $121,869 0.177 $687,282
85 kg $137,810 0.177 $777,186
95 kg $153,752 0.177 $867,090
Starting Age    
35 years old $122,293 0.178 $686,130
45 years old $122,077 0.178 $686,759
55 years old $121,504 0.177 $687,371
65 years old $119,999 0.176 $683,643
75 years old $116,182 0.170 $683,219
Discount rate    
0% $126,340 0.185 $682,390
3% $123,542 0.180 $685,346
Model time horizon    
   1 year $59,546 0.078 $764,917
   3 years $102,457 0.146 $702,569
   5 years $121,869 0.177 $687,282
   10 years $139,986 0.209 $670,396
   20 years $143,690 0.218 $658,267
Incremental IVIG utility gain = 0.25 $121,869 0.364 $335,038
Assume corticosteroid patients switch to IVIG after adverse event $113,444 0.166 $682,309
Relapse rate for IVIG not extrapolated beyond 25 weeks $173,189 0.257 $672,616
Maintenance IVIG dose and frequency    
   1.0 mg/kg every 3 weeks $121,869 0.177 $687,282
   1.0 mg/kg every 6 weeks $65,304 0.177 $368,284
   1.0 mg/kg every 8 weeks $51,163 0.177 $288,535
   0.4 mg/kg every 3 weeks $55,661 0.177 $313,905
   0.4 mg/kg every 6 weeks $32,200 0.177 $181,595
   0.4 mg/kg every 8 weeks $26,335 0.177 $148,518