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Table 3 Cost per event or state used in the analysis, expressed in 2005 values (€)

From: Cost-effectiveness of pioglitazone in type 2 diabetes patients with a history of macrovascular disease: a German perspective

 

Event cost (€)

Follow up cost (€)

Reference(s)

Death (all causes)

0.00

0.00

Assumed

CVD death

0.00

0.00

Assumed to be zero as no published value was found

MI (excluding silent MI)

8,634.93

3,647,32

[49]

Silent MI

0.00

0.00

Assumed

Acute coronary syndrome (ACS)

3,120.92

0.00

[50]

CABG only

12,435.81

0.00

[51]

PCI only

4,360.03

0.00

[51]

Stroke

10,523.62

6,178.06

[49] and [52]

Leg amputation (major, above ankle)

15,405.10

3,303.92

[49] and [53]

Bypass surgery/revascularization of leg

6,268.09

0.00

[50]

Transient ischemic attack (TIA)

2,353.52

0.00

[50]

Retinal photocoagulation

1,862.28

340.33

[50]

Severe vision loss (SVL)

10,660.98

10,660.98

[54]

Hospitalization for CHF

2,272.97

0.00

[55]

Non-serious heart failure

34.51

0.00

Assumed to be same as a physician visit cost (as CVD medication costs are already captured)

Oedema

34.51

0.00

[56]

Peripheral vascular disease (onset)

2,635.85

0.00

[56]

Haemodialysis

59,248.85

59,248.85

[57]

Peritoneal dialysis

47,198.66

47,198.66

[57]

Kidney transplant

69,504.00

11,116.77

[58]

Cataract extraction

1,347.78

0.00

[59]

Neuropathy, onset

3,930.36

0.00

[60]

Uninfected ulcer

894.22

0.00

[60]

Infected ulcer

1,818.58

0.00

[60]

Gangrene

3,247.62

0.00

[60]

Major hypoglycaemic event

2,555

0.00

[34]

  1. CVD = cardiovascular disease; MI = myocardial infarction; CABG = coronary artery bypass graft; PCI = percutaneous coronary intervention; CHF = congestive heart failure. Where necessary costs were inflated to 2005 values