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Table 4 Sensitivity analysis: cost per life saved for different values of model parameters

From: Cost effectiveness of community-based therapeutic care for children with severe acute malnutrition in Zambia: decision tree model

 

Parameter values

Incremental cost effectiveness ratio ($ per life saved)

 

Base

Minus 50%

Plus 50%

Low

High

Range

Outcome probabilities

      

Death rate within a year without CTC HIV- *

0.18

0.09**

0.27

17502**

927

16576

Relative risk of death if HIV+, no CTC *

2

1

3

2300

1426

874

Refer to hospital from CTC

0.059

0.030

0.089

1479

2100

622

Death within a year if recover with CTC

0.0364

0.0182

0.0546

1520

2091

571

HIV prevalence*

0.15

0.075

0.225

1994

1575

419

Death during CTC

0.026

0.013

0.039

1586

1978

392

Death rate in hospital

0.37

0.185

0.555

1608

1944

337

Death rate among defaulters

0.045

0.022

0.067

1703

1821

118

Default from CTC

0.173

0.087

0.260

1721

1802

82

Costs

      

Weeks of CTC – Recovered

6.6

3.3

9.9

1419

2101

682

RUTF per Kg ($)

6.20

3.10

9.30

1445

2075

630

Mean Kg of RUTF per child per week

1.90

0.95

2.85

1445

2075

630

Valid cost per child ($)

68.69

34

103

1462

2058

597

Hospital cost per day ($)

41.35

20.68

62.03

1612

1908

297

Days in hospital

14

7

21

1612

1908

297

Costs per health centre visit ($)

4.24

2.12

6.36

1647

1873

227

Weeks of CTC – Defaulted

5.1

2.6

7.7

1699

1821

123

Weeks of CTC – Referred

4.8

2.4

7.2

1740

1780

39

Weeks of CTC – Died

3.6

1.8

5.4

1754

1767

13

Community mobilisation per child $

1.06

0.5

1.6

1755

1765

9

  1. * CTC is more cost effective if these parameters are greater.
  2. ** note higher mortality with CTC than with no care