Table 1 The interventions, generic drug names and dosages for the drug combinations considered in the analysis.
Intervention | Generic drug | Daily dose |
|---|---|---|
Aspirin (Asa) | Acetylsalicylic acid | 75 mg |
Diuretic drug (Diu) | Hydrochlorothiazide | 25 mg |
β-blocker (Bet) | Atenolol | 50 mg |
Calcium antagonist (Cab) | Nifedepine | 40 mg |
Statin (Sta) | Lovastatin | 40 mg |
Aspirin + Diuretic drug (AsaDiu) | Acetylsalicylic acid | 75 mg |
Hydrochlorothiazide | 25 mg | |
Aspirin + β-blocker (AsaBet) | Acetylsalicylic acid | 75 mg |
Atenolol | 50 mg | |
Diuretic drug + β-blocker (DiuBet) | Hydrochlorothiazide | 25 mg |
Atenolol | 50 mg | |
Aspirin + Diuretic drug + β-blocker (AsaDiuBet) | Acetylsalicylic acid | 75 mg |
Hydrochlorothiazide | 25 mg | |
Atenolol | 50 mg | |
Aspirin + Diuretic drug + Statin (AsaDiuSta) | Acetylsalicylic acid | 75 mg |
Hydrochlorothiazide | 25 mg | |
Lovastatin | 40 mg | |
Diuretic drug + β-blocker + Statin (DiuBetSta) | Hydrochlorothiazide | 25 mg |
Atenolol | 50 mg | |
Lovastatin | 40 mg | |
Aspirin + β-blocker + Statin (AsaBetSta) | Acetylsalicylic acid | 75 mg |
Atenolol | 50 mg | |
Lovastatin | 40 mg | |
Aspirin + Diuretic drug + β-blocker + Statin (AsaDiuBetSta) | Acetylsalicylic acid | 75 mg |
Hydrochlorothiazide | 25 mg | |
Atenolol | 50 mg | |
Lovastatin | 40 mg | |
Hypothetical polypill | Acetylsalicylic acid | 75 mg |
Hydrochlorothiazide | 12.5 mg | |
Atenolol | 25 mg | |
Nifedepine | 20 mg | |
Lovastatin | 20 mg | |
Folic acid | 1 mg |