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Table 5 Incremental costs, effects, and cost-effectiveness analysis

From: Cost-effectiveness of a nurse-led telemonitoring intervention based on peak expiratory flow measurements in asthmatics: results of a randomised controlled trial

Base case

Adults

Children

Incremental costs

Health care costs

€508

€605

(2.5th–97.5th percentile)

(-114 to 1,118)

(319 to 862)

Societal costs

€1,026

€609

(2.5th–97.5th percentile)

(231 to 1,889)

(312 to 864)

Incremental utility adjusted for baseline differences by multiple regression

EQ-5D QALY1

0.03

0.01

(2.5th–97.5th percentile)

(0.00 to 0.07)

(0.00 to 0.02)

SF-6D QALY1

-0.01

     

(2.5th–97.5th percentile)

(-0.07 to 0.03)

-

Incremental cost effectiveness ratio

Health care perspective EQ-5D

€15,366/QALY gained

€58,726/QALY gained

Distributions on CEA plane

origin

NE

NW

SW

SE

origin

NE

NW

SW

SE

 

0%

91%

3%

0%

5%

0%

98%

2%

0%

0%

Health care perspective SF-6D

inferior

-

Distributions on CEA plane

origin

NE

NW

SW

SE

     
 

0%

17%

77%

5%

1%

     

Societal perspective EQ-5D

€31,035/QALY gained

€59,071/QALY gained

Distributions on CEA plane

origin

NE

NW

SW

SE

origin

NE

NW

SW

SE

 

0%

96%

4%

0%

1%

0%

98%

2%

0%

0%

Societal perspective SF-6D

inferior

-

Distributions on CEA plane

origin

NE

NW

SW

SE

     
 

0%

17%

83%

0%

0%

     

Sensitivity analysis (minus asthma monitor costs)

Incremental costs

Health care costs

€58

€156

(2.5th–97.5th percentile)

(-544 to 671)

(-137 to 411)

Societal costs

€576

€159

(2.5th–97.5th percentile)

(-257 to 1,423)

(-142 to 417)

Incremental cost effectiveness ratio

Health care perspective EQ-5D

€1,759/QALY gained

€15,092/QALY gained

Distributions on CEA plane

origin

NE

NW

SW

SE

origin

NE

NW

SW

SE

 

0%

91%

3%

0%

5%

0%

84%

1%

0%

15%

Health care perspective SF-6D

inferior

-

Distributions on CEA plane

origin

NE

NW

SW

SE

     
 

0%

9%

46%

38%

7%

     

Societal perspective EQ-5D

€17,427/QALY gained

€15,438/QALY gained

Distributions on CEA plane

origin

NE

NW

SW

SE

origin

NE

NW

SW

SE

 

0%

89%

3%

0%

8%

0%

85%

2%

0%

13%

Societal perspective SF-6D

inferior

-

Distributions on CEA plane

origin

NE

NW

SW

SE

     
 

0%

14%

76%

8%

2%

     

Sensitivity analysis (school costs included in analysis)

Incremental costs

Societal costs

€542

(2.5th–97.5th percentile)

(196 to 849)

Incremental cost effectiveness ratio

Societal perspective EQ-5D

€52,618/QALY gained

Distributions on CEA plane

     

origin

NE

NW

SW

SE

      

0%

97%

3%

0%

0%

  1. Costs year 2002 in euro.
  2. ICER = Incremental Cost-effectiveness Ratio.
  3. Percentiles based on bootstrap procedure with 5000 replicates.
  4. 1 Utility scores at follow-up measurements are adjusted for between group baseline difference using the multiple regression method.