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Table 3 Frequency of Use of Pain Medications

From: Resource use among patients with diabetes, diabetic neuropathy, or diabetes with depression

Pain Medications

Diabetes (N = 55,972)

Diabetic Neuropathy (N = 2,146)

Diabetes and Depression (N = 2,379)

P-Value

 

N

%

N

%

N

%

DM v DN

DM v DD

DN v DD

Antidepressants

         

   SSRI

3,376

6.03

536

24.98

1,346

56.58

*

*

*

   Tricyclic

1,884

3.37

366

17.05

354

14.88

*

*

**

   Venlafaxine

271

0.48

58

2.70

216

9.08

*

*

*

   Bupropion

750

1.34

109

5.08

333

14.00

*

*

*

   Other Antidepressant

641

1.15

127

5.92

414

17.40

*

*

*

   Any Antidepressant

5,979

10.68

887

41.33

1,715

72.09

*

*

*

Anticonvulsant

         

   Gabapentin

867

1.55

286

13.33

197

8.28

*

*

*

   Other Anticonvulsant

911

1.63

137

6.38

273

11.48

*

*

*

   Any Anticonvulsant

1,669

2.98

388

18.08

414

17.40

*

*

0.4693

Skeletal-Muscle Relaxants

3,623

6.47

349

16.26

404

16.98

*

*

0.6165

Non-Narcotics

1,018

1.82

88

4.10

134

5.63

*

*

**

Narcotics

         

   Oxycodone

2,789

4.98

370

17.24

353

14.84

*

*

***

   Tramadol

1,043

1.86

129

6.01

144

6.05

*

*

0.9949

   Codeine

3,128

5.59

300

13.98

306

12.86

*

*

0.2611

   Hydrocodone-Acetaminophen

5,545

9.91

528

24.60

645

27.11

*

*

***

   Proxyphene

3,374

6.03

350

16.31

369

15.51

*

*

0.5303

   Other Narcotics

1,051

1.88

121

5.64

150

6.31

*

*

0.2740

   Any Narcotics

12,383

22.12

1,065

44.63

1,152

48.42

*

*

0.6036

NSAIDs

         

   Cox-2

4,445

7.94

355

16.54

407

17.11

*

*

0.7753

   Other NSAID

10,005

17.88

761

35.46

823

34.59

*

*

0.7367

   Any NSAID

12,839

22.94

938

43.71

1,040

43.72

*

*

1.00

  1. *P-value ≤ 0.0001; **P-value ≤ 0.001; ***P-value ≤ 0.05
  2. P values based on Tukey-Kramer method to adjust for multiple comparisons.