From: Resource use among patients with diabetes, diabetic neuropathy, or diabetes with depression
Pain Medications | Diabetes (N = 55,972) | Diabetic Neuropathy (N = 2,146) | Diabetes and Depression (N = 2,379) | P-Value | |||||
---|---|---|---|---|---|---|---|---|---|
 | N | % | N | % | N | % | DM v DN | DM v DD | DN v DD |
Antidepressants | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   SSRI | 3,376 | 6.03 | 536 | 24.98 | 1,346 | 56.58 | * | * | * |
   Tricyclic | 1,884 | 3.37 | 366 | 17.05 | 354 | 14.88 | * | * | ** |
   Venlafaxine | 271 | 0.48 | 58 | 2.70 | 216 | 9.08 | * | * | * |
   Bupropion | 750 | 1.34 | 109 | 5.08 | 333 | 14.00 | * | * | * |
   Other Antidepressant | 641 | 1.15 | 127 | 5.92 | 414 | 17.40 | * | * | * |
   Any Antidepressant | 5,979 | 10.68 | 887 | 41.33 | 1,715 | 72.09 | * | * | * |
Anticonvulsant | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   Gabapentin | 867 | 1.55 | 286 | 13.33 | 197 | 8.28 | * | * | * |
   Other Anticonvulsant | 911 | 1.63 | 137 | 6.38 | 273 | 11.48 | * | * | * |
   Any Anticonvulsant | 1,669 | 2.98 | 388 | 18.08 | 414 | 17.40 | * | * | 0.4693 |
Skeletal-Muscle Relaxants | 3,623 | 6.47 | 349 | 16.26 | 404 | 16.98 | * | * | 0.6165 |
Non-Narcotics | 1,018 | 1.82 | 88 | 4.10 | 134 | 5.63 | * | * | ** |
Narcotics | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   Oxycodone | 2,789 | 4.98 | 370 | 17.24 | 353 | 14.84 | * | * | *** |
   Tramadol | 1,043 | 1.86 | 129 | 6.01 | 144 | 6.05 | * | * | 0.9949 |
   Codeine | 3,128 | 5.59 | 300 | 13.98 | 306 | 12.86 | * | * | 0.2611 |
   Hydrocodone-Acetaminophen | 5,545 | 9.91 | 528 | 24.60 | 645 | 27.11 | * | * | *** |
   Proxyphene | 3,374 | 6.03 | 350 | 16.31 | 369 | 15.51 | * | * | 0.5303 |
   Other Narcotics | 1,051 | 1.88 | 121 | 5.64 | 150 | 6.31 | * | * | 0.2740 |
   Any Narcotics | 12,383 | 22.12 | 1,065 | 44.63 | 1,152 | 48.42 | * | * | 0.6036 |
NSAIDs | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   Cox-2 | 4,445 | 7.94 | 355 | 16.54 | 407 | 17.11 | * | * | 0.7753 |
   Other NSAID | 10,005 | 17.88 | 761 | 35.46 | 823 | 34.59 | * | * | 0.7367 |
   Any NSAID | 12,839 | 22.94 | 938 | 43.71 | 1,040 | 43.72 | * | * | 1.00 |