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Table 2 NNT and Drug Costs by Adverse Events

From: A cost-minimization analysis of diuretic-based antihypertensive therapy reducing cardiovascular events in older adults with isolated systolic hypertension

Event

Placebo risk

Treatment risk

ARR

NNT

(95% CI)

5-Year NNT

5-year Rx Cost Per Patient

Total Cost

Incremental Cost

Death

0.1002

0.0858

0.0144

69

(31 – 319)

62

$456

$28,284

$13,230

CVD

0.1746

0.1147

0.0599

17

(12 – 26)

15

$456

$6,843

-

Stroke

0.0705

0.0433

0.0272

37

(24 – 76)

33

$456

$15,055

$0 (base)

MI

0.0312

0.0202

0.011

91

(48 – 740)

82

$456

$37,408

$22,354

CHF

0.0397

0.0198

0.0199

50

(33 – 103)

45

$456

$20,529

$5,474