A cost-minimization analysis of diuretic-based antihypertensive therapy reducing cardiovascular events in older adults with isolated systolic hypertension

Table 1 Estimated Drug Acquisition Costs of The SHEP Treatment Protocol

Drug Category	Drug Cost Per Patient in 1 Year	Proportion	Drug Cost Per Patient in 5 years
step1 dose1 (chlorthalidone 12.5 mg/d)	$10.24	0.43
step1 dose2 (chlorthalidone 25 mg/d)	$20.48	0.23
step2 dose1 (chlorthalidone 25 mg/d plus atenolol 25 mg/d or reserpine 0.05 mg/d)	$222.45	0.16
step2 dose2 (chlorthalidone 25 mg/d plus atenolol 50 mg/d or reserpine 0.1 mg/d)	$221.93	0.17
Weighted SHEP Rx	$83.29	0.91
KCL	$88.33	0.09
Weighted SHEP Rx including KCL	$91.24		$456
SD	$101.78

ISSN: 1478-7547