| Metformin | Combination | Difference |
---|---|---|---|
Cumulative cost (mean per patient) | Â | Â | Â |
   Complications | £3,548 | £3,084 | £-464 |
   Total | £5,093 | £7,159 | £2,066 |
Survival (mean, years) | Â | Â | Â |
   Life years (discounted) | 13.5 (11.7) | 13.9 (12.1) | 0.39 (0.32) |
   Quality Adjusted (discounted) | 12.2 (10.7) | 12.6 (11.0) | 0.46 (0.37) |
Cost-effectiveness | Â | Â | Â |
   Cost per LYG (discounted LYG) |  |  | £5,403 (6,772) |
   Cost per QALY (discounted QALY) |  |  | £4,500 (5,609) |