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Table 3 Health benefits and costs for metformin and the combination of metformin with nateglinide

From: Health and economic impact of combining metformin with nateglinide to achieve glycemic control: Comparison of the lifetime costs of complications in the U.K

 

Metformin

Combination

Difference

Cumulative cost (mean per patient)

   

   Complications

£3,548

£3,084

£-464

   Total

£5,093

£7,159

£2,066

Survival (mean, years)

   

   Life years (discounted)

13.5 (11.7)

13.9 (12.1)

0.39 (0.32)

   Quality Adjusted (discounted)

12.2 (10.7)

12.6 (11.0)

0.46 (0.37)

Cost-effectiveness

   

   Cost per LYG (discounted LYG)

  

£5,403 (6,772)

   Cost per QALY (discounted QALY)

  

£4,500 (5,609)

  1. LYG = Life Year Gained QALY = Quality Adjusted Life Year