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Table 4 Resource consumption per patient, during each 4 weeks, by HAM-A score

From: A cost-utility analysis of pregabalin versus venlafaxine XR in the treatment of generalized anxiety disorder in Portugal

 

HAM-A Score

≤ 9

10 - 15

16 - 24

≥ 25

Number of doctor visits

  Number of general practitioner visits

0.6

0.8

1.2

1.6

  Number of psychiatrist visits

0.08

0.1

0.2

0.4

  Number of other specialist visits

0.15

0.2

0.3

0.4

Number of psychologist visits

0

0

0.1

0.1

Number of emergency attendances

0.05

0.1

0.15

0.25

Number of exams and analyses

  Number of electrocardiograms

0.3

0.4

0.6

0.8

  Number of blood analyses

0.3

0.4

0.6

0.8

  Number of thyroid functions

0

0

0.05

0.05

Number of inpatient stays

0

0

0

0.004

Concomitant drugs for both alternatives

  Proportion taking antipsychotics

0%

0%

5%

10%

  Most prescribed

Quetiapine

  Mean daily dose

-

-

100 mg qd

100 mg qd

  Proportion taking hypnotics

0%

0%

10%

20%

  Most prescribed

Zolpidem

  Mean daily dose

-

-

10 mg qd

10 mg qd

Concomitant drugs for venlafaxine XR

  Proportion taking anxiolytics

100%

100%

100%

100%

  Most prescribed

Alprazolam

  Mean daily dose

0.5 mg qd

0.5 mg qd

0.5 mg tid

1 mg tid

Concomitant drugs for pregabalin

  Proportion taking antidepressants

10%

25%

50%

50%

  Most prescribed

Paroxetine

  Mean daily dose

10 mg qd

10 mg qd

20 mg qd

20 mg qd

  1. Source: Expert panel.
  2. Blood analyses include glucose, gamma glutamyl transferase, creatinine, haemogram, sedimentation velocity, aspartate and alanine aminotransferase, urea and urinalysis.