Table 4 Cost of 15-week ESAs treatment (6-cycles chemotherapy) for responder & non responder patients receiving originators or biosimilars per Hb level
Responders | Non responders | Responders | Non responders | Cost difference for responders originators vs. Biosimilars (€) | Cost difference for non responders originators vs. Biosimilars (€) | Total difference originators vs. Biosimilars (€) | |||
|---|---|---|---|---|---|---|---|---|---|
HB Nadir (g/dl) | % of patients per Hb level | Number of Greek patients treated with ESAs per Hb Level | Cost of 15 weeks treatment with originator ESAs (€) | Cost of 15 weeks treatment with originator ESAs (€) | Cost of 15 weeks treatment with Biosimilar ESAs (€) | Cost of 15 weeks treatment with Biosimilar ESAs (€) | |||
<9 | 33.5 | 855 | 1.233.547 | 2.144.861 | 1.120.816 | 1.713.324 | 112.731 | 431.537 | 544.268 |
9.0-9.9 | 27.5 | 701 | 1.012.613 | 1.760.707 | 920.072 | 1.406.460 | 92.541 | 354.247 | 446.787 |
10.0-10.9 | 24.7 | 630 | 909.511 | 1.581.435 | 826.392 | 1.263.257 | 83.118 | 318.178 | 401.296 |
11.0-11.9 | 9.5 | 242 | 349.812 | 608.244 | 317.843 | 485.868 | 31.969 | 122.376 | 154.345 |
>12.0 | 4.8 | 122 | 176.747 | 307.323 | 160.594 | 245.491 | 16.153 | 61.832 | 77.985 |
Total | 100 | 2.551 | 3.682.229 | 6.402.570 | 3.345.718 | 5.114.400 | 336.511 | 1.288.170 | 1.624.681 |