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Table 2 Costs for acute myocardial infarction, 2003–2007, Germany

From: Cost of clinical events in health economic evaluations in Germany: a systematic review

Study Model type Specification of disease severity First cycle Costs covered Follow-up cycles
    Time horizon Unit cost (€) Number of sourcesa Direct costsb Not specified Time horizon Unit cost (€) Number of sourcesa
       Hosp Rehab Other     
Year of costing: 2003
Annemans L. Int J Clin Pract 2006; 60(9): 1129–37 [8] Markov model Fatal MI Not specified 2,880 1     Yes No follow-up costs considered
Lamotte M. Pharmacoeconomics 2006; 24(2): 155–69 [16] Markov model Fatal MI Not specified 2,880 NA Yes     No follow-up costs considered
Annemans L. Int J Clin Pract 2006; 60(9): 1129–37 [8] Markov model Non-fatal MI Not specified 3,123 1     Yes Annual follow-up costs 1,907 1
Lamotte M. Pharmacoeconomics 2006; 24(2): 155–69 [16] Markov model Non-fatal MI Not specified 3,123 NA Yes     Annual follow-up costs 1,907 1
Liebl A. Gesund ökon Qual Manag 2006; 11: 105–11 [18] Decision tree MI Not specified 5,878 1 Yes     Follow-up: rehabilitation 1,261 > 1
           Annual follow-up costs 1,012 > 1
Year of costing: 2004
Lamotte M. Pharmacoeconomics 2006; 24(8): 783–95 [17] Decision tree Fatal MI Acute period 2,880 1 Yes     No follow-up costs considered
   Non-fatal MI Acute period 3,123 1 Yes     No follow-up costs considered
Gandjour A. Health Policy 2007; 83(2–3): 257–67 [14] Markov model MI First 12 months 4,618 > 1     Yes Post-year 1 2,014 > 1
Brüggenjürgen B. Eur J Health Econ 2007; 8(1): 51–7 [12] Markov model MI First 12 months 11,241 1 Yes Yes Yes   Annual follow-up costs 1,006 1
Roze S. Curr Med Res Opin 2006; 22(7): 1415–24 [23] Semi-Markov model MI Year of event 15,011 > 1     Yes Annual follow-up costs 1,168 1
Year of costing: 2005
Scherbaum WA. Cost Eff Resour Alloc 2009; 7: 9 [25] Semi-Markov model Silent MI Year of event 0 NA     Yes No follow-up costs considered   
Berg J. Clin Ther 2007; 29(6): 1184–202 [9] Decision tree and Markov model MI Month 1 6,799 > 1     Yes Months 2–12 5,129 1
Berger K. Curr Med Res Opin 2008; 24(1): 267–74 [11] Markov model MI Initial treatment 7,522 1    Yes   First 6 months after event 2,235 1
           Second 6 months after event 1,484 1
           Subsequent 6- month intervals 759 1
Scherbaum WA. Cost Eff Resour Alloc 2009; 7: 9 [25] Semi-Markov model Excluded silent MI Year of event 8,635 1     Yes Annual follow-up costs 3,647 1
Weber CJ. Diabetes Sci Technol 2007; 1(5): 676–84 [28] Markov model MI Year of event 16,767 1     Yes Year after event 1,253 1
Year of costing: 2006
Valentine WJ. Adv Ther 2008; 25(6): 567–84 [27] Semi-Markov model MI Year of event 15,816 > 1     Yes Annual follow-up costs 1,230 > 1
Schaufler TM. Gesund ökon Qual Manag 2009; 14: 71–5 [24] Markov model MI First 12 months 17,556 1     Yes Annual follow-up costs 2,323 1
Berg J. Curr Med Res Opin 2008; 24(7): 2089–101 [10] Decision tree and Markov model MI Month 1 6,899 > 1     Yes Months 2–12 5,204 1
           Annual follow-up costs 2,035 1
Year of costing: 2007
Mittendorf T. Diabetes Obes Metab 2009; 11(11): 1068–79 [19] Semi-Markov model MI Year of event 8,614 1     Yes Annual follow-up costs 1,292 NA
Schwander B. Value Health 2009; 12(6): 857–71 [26] Markov model MI First 12 months 11,683 > 1     Yes Annual follow-up costs 2,803 > 1
  1. a Number of data sources from which unit costs were retrieved.
  2. b No indirect unit costs could be retrieved.
  3. hosp = hospital; MI = myocardial infarction; NA = not available; rehab = rehabilitation.