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Table 2 Costs for acute myocardial infarction, 2003–2007, Germany

From: Cost of clinical events in health economic evaluations in Germany: a systematic review

Study

Model type

Specification of disease severity

First cycle

Costs covered

Follow-up cycles

   

Time horizon

Unit cost (€)

Number of sourcesa

Direct costsb

Not specified

Time horizon

Unit cost (€)

Number of sourcesa

      

Hosp

Rehab

Other

    

Year of costing: 2003

Annemans L. Int J Clin Pract 2006; 60(9): 1129–37 [8]

Markov model

Fatal MI

Not specified

2,880

1

   

Yes

No follow-up costs considered

Lamotte M. Pharmacoeconomics 2006; 24(2): 155–69 [16]

Markov model

Fatal MI

Not specified

2,880

NA

Yes

   

No follow-up costs considered

Annemans L. Int J Clin Pract 2006; 60(9): 1129–37 [8]

Markov model

Non-fatal MI

Not specified

3,123

1

   

Yes

Annual follow-up costs

1,907

1

Lamotte M. Pharmacoeconomics 2006; 24(2): 155–69 [16]

Markov model

Non-fatal MI

Not specified

3,123

NA

Yes

   

Annual follow-up costs

1,907

1

Liebl A. Gesund ökon Qual Manag 2006; 11: 105–11 [18]

Decision tree

MI

Not specified

5,878

1

Yes

   

Follow-up: rehabilitation

1,261

> 1

          

Annual follow-up costs

1,012

> 1

Year of costing: 2004

Lamotte M. Pharmacoeconomics 2006; 24(8): 783–95 [17]

Decision tree

Fatal MI

Acute period

2,880

1

Yes

   

No follow-up costs considered

  

Non-fatal MI

Acute period

3,123

1

Yes

   

No follow-up costs considered

Gandjour A. Health Policy 2007; 83(2–3): 257–67 [14]

Markov model

MI

First 12 months

4,618

> 1

   

Yes

Post-year 1

2,014

> 1

Brüggenjürgen B. Eur J Health Econ 2007; 8(1): 51–7 [12]

Markov model

MI

First 12 months

11,241

1

Yes

Yes

Yes

 

Annual follow-up costs

1,006

1

Roze S. Curr Med Res Opin 2006; 22(7): 1415–24 [23]

Semi-Markov model

MI

Year of event

15,011

> 1

   

Yes

Annual follow-up costs

1,168

1

Year of costing: 2005

Scherbaum WA. Cost Eff Resour Alloc 2009; 7: 9 [25]

Semi-Markov model

Silent MI

Year of event

0

NA

   

Yes

No follow-up costs considered

  

Berg J. Clin Ther 2007; 29(6): 1184–202 [9]

Decision tree and Markov model

MI

Month 1

6,799

> 1

   

Yes

Months 2–12

5,129

1

Berger K. Curr Med Res Opin 2008; 24(1): 267–74 [11]

Markov model

MI

Initial treatment

7,522

1

  

Yes

 

First 6 months after event

2,235

1

          

Second 6 months after event

1,484

1

          

Subsequent 6- month intervals

759

1

Scherbaum WA. Cost Eff Resour Alloc 2009; 7: 9 [25]

Semi-Markov model

Excluded silent MI

Year of event

8,635

1

   

Yes

Annual follow-up costs

3,647

1

Weber CJ. Diabetes Sci Technol 2007; 1(5): 676–84 [28]

Markov model

MI

Year of event

16,767

1

   

Yes

Year after event

1,253

1

Year of costing: 2006

Valentine WJ. Adv Ther 2008; 25(6): 567–84 [27]

Semi-Markov model

MI

Year of event

15,816

> 1

   

Yes

Annual follow-up costs

1,230

> 1

Schaufler TM. Gesund ökon Qual Manag 2009; 14: 71–5 [24]

Markov model

MI

First 12 months

17,556

1

   

Yes

Annual follow-up costs

2,323

1

Berg J. Curr Med Res Opin 2008; 24(7): 2089–101 [10]

Decision tree and Markov model

MI

Month 1

6,899

> 1

   

Yes

Months 2–12

5,204

1

          

Annual follow-up costs

2,035

1

Year of costing: 2007

Mittendorf T. Diabetes Obes Metab 2009; 11(11): 1068–79 [19]

Semi-Markov model

MI

Year of event

8,614

1

   

Yes

Annual follow-up costs

1,292

NA

Schwander B. Value Health 2009; 12(6): 857–71 [26]

Markov model

MI

First 12 months

11,683

> 1

   

Yes

Annual follow-up costs

2,803

> 1

  1. a Number of data sources from which unit costs were retrieved.
  2. b No indirect unit costs could be retrieved.
  3. hosp = hospital; MI = myocardial infarction; NA = not available; rehab = rehabilitation.