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Table 1 List of Model Variables for Base Case Scenario

From: Cost-effectiveness of surgical treatment of thumb carpometacarpal joint arthritis: a value of information study

 

Base

Low

High

Source

Distribution

Population

Age at time of injury

62

61

64

Thorkildsen and Rokkum(28)

Uniform

Life Expectancy

86

82

98

Center for Disease Control and Prevention (CDC)(27)

Uniform, but 1 year above age at time of injury

Complication Rates

Conservative Management

Unresolved pain (failure)

1

0.95

1

 

 N/A

Trapeziectomy

CRPS†

0.029

0.016

0.095

Davis, Brady, and Dias(13); Salem and Davis(20)

Beta

Tendon rupture

0

0

0

 

N/A

Unresolved pain (failure)

0.079

0.04

0.13

De Smet et al.(17)

Beta

LRTI‡

     

CRPS†

0.04

0.018

0.08

Davis, Brady, Barton, Lunn, and Burke(15); Gangopadhyay et al(12)

Beta

Tendon rupture

0.043

0.043

0.043

Belcher and Nicholl(10)

Beta

Unresolved pain (failure)

0.066

0.01

0.13

De Smet et al.(17)

Beta

Costs

Direct costs

Conservative Management

0

0

0

  

Trapeziectomy (CPT 25,210)

Physician Fee

508.39

448.62

702.02

2020 cm National Physician Fee Schedule(29) (national payment amount base, min MAC, max MAC)

Truncated Normal (> 0)

Anesthesia Fees

151

135.9

166.1

 cm(29)

Truncated Normal (> 0)

Facility Fees

2830.4

2547.36

3113.44

Medicare and HCUP (2020 OPPS)(23)

Truncated Normal (> 0)

Hand Therapy Cost

477.28

432.36

673.75

Indiana Hand Center(22),2020 cm National Physician Fee Schedule(29) (national payment amount base, min MAC, max MAC)

Truncated Normal (> 0)

LRTI‡ (CPT 25,447)

Physician Fee

854.53

756.87

1181.55

2020 cm National Physician Fee Schedule(29) (national payment amount base, min MAC, max MAC)

Truncated Normal (> 0)

Anesthesia Fees

194

174.6

213.4

 cm(29)

Truncated Normal (> 0)

Facility Fees

2830.4

2547.36

3113.44

Medicare and HCUP (2020 OPPS)(23, 29)

Truncated Normal (> 0)

Hand Therapy Cost

477.28

432.36

673.75

Indiana Hand Center(22), 2020 cm National Physician Fee Schedule(29) (national payment amount base, min MAC, max MAC)

Truncated Normal (> 0)

Complications (Cost)

CRPS†

Physician Fee

444

399.6

488.4

2020 cm National Physician Fee Schedule(29) (national payment amount base, min MAC, max MAC)

Truncated Normal (> 0)

Tendon repair (CPT 26,356)

Physician Fee

822.05

739.845

904.255

2020 cm National Physician Fee Schedule(29) (national payment amount base, min MAC, max MAC)

Truncated Normal (> 0)

Anesthesia Fee

124.7233

112.251

137.1957

 cm(29)

Truncated Normal (> 0)

Hospital Fee

2623.34

2361.006

2885.674

Medicare and HCUP (2020 OPPS)(23, 29)

Truncated Normal (> 0)

Wage Calculations

Average annual mean

51,960

10,000

250,000

Bureau of Labor and Statistics(30)

Truncated Normal (> 0)

Time off for recovery and rehab (days)

Conservative Management

0

0

0

Indiana Hand Center(22)

N/A

Trapeziectomy

30

14

84

Indiana Hand Center(22)

Truncated Normal (> 0)

LRTI‡

30

14

84

Indiana Hand Center(22)

Truncated Normal (> 0)

Retirement age

66

60

70

Social Security(44)

Truncated Normal (> 0)

Discount Rate

0.03

0

0.07

 N/A

N/A

Utilities

Baseline

Conservative Management

0.675

0.26

0.8

Lane et al.(25)

Normal

Relative increases for trapeziectomy and LRTI‡

Trapeziectomy Increase

0.16

0.14

0.19

Lane et al.(25)

Normal

LRTI‡ Increase

0.14

0.11

0.17

Lane et al.(25)

Normal

  1. †CRPS: Complex Regional Pain Syndrome
  2. ‡LRTI: Ligament Reconstruction and Tendon Interposition
  3. CMS: Center for Medicare and Medicaid Services
  4. All distributions are parameterized with means equal to the base case and standard deviations of ¼ the range between the low and high. If a distribution is listed as N/A, the parameter is not varied in the probabilistic sensitivity analysis or value of information analysis