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Table 1 Key costs and inputs to the economic model

From: Estimating outcomes and cost effectiveness using a single-arm clinical trial: ofatumumab for double-refractory chronic lymphocytic leukemia

Parameter

Value

Hazard ratio: overall survival, BSC vs. ofatumumab

1.8727

Hazard ratio: progression-free survival, BSC vs. ofatumumab

1.9608

Ofatumumab: cost of therapy initiation

£2047

Ofatumumab: cost per 100 mg vial

£182

Ofatumumab: concomitant medication cost

£104

Ofatumumab: cost per chemotherapy administration

£203

BSC: cost of therapy initiation

£1470

All therapies: cost per month of routine management

£158

Utility: progression-free survival

0.65

Utility: post-progression survival

0.47

  1. BSC best supportive care