Table 4 Comparison of bootstrapped mean difference (MD) in baseline and adjusted mean difference in post procedure and end of follow up costs by wave: intervention v control
Wave | Baseline (n = 3818) | Post procedure (n = 2940) | End of follow up (n = 2588) | ||||||
|---|---|---|---|---|---|---|---|---|---|
|  | Bootstrapped MD (I – C) | p | 95% CI | Adjusted MD (I – C) | p | 95% CI | Adjusted MD (I – C) | p | 95% CI |
Primary care cost (ÂŁ) | |||||||||
W1 | -ÂŁ6.74 | 0.15 | -19.80 to 6.00 | ÂŁ5.15 | 0.33 | -5.28 to 15.58 | -ÂŁ5.97 | 0.28 | -16.72 to 4.79 |
W2 | ÂŁ5.35 | 0.75 | -7.19 to 24.40 | -ÂŁ2.47 | 0.69 | -15.92 to 9.99 | -ÂŁ1.28 | 0.87 | -16.80 to 14.20 |
W3 | ÂŁ3.34 | 0.71 | -7.90 to 16.11 | -ÂŁ21.6 | 0.00 | -32.50 to -10.80 | -ÂŁ8.88 | 0.34 | -27.10 to 9.31 |
W4 | -ÂŁ19.30 | 0.02 | -43.80 to -4.22 | -ÂŁ9.16 | 0.11 | -20.23 to 1.92 | ÂŁ0.87 | 0.90 | -12.50 to 14.30 |
W5 | -ÂŁ7.28 | 0.17 | -25.20 to 5.90 | -ÂŁ1.42 | 0.76 | -10.65 to 7.82 | -ÂŁ35.6 | 0.06 | -71.90 to 0.08 |
Secondary care cost (ÂŁ) | |||||||||
W1 | -ÂŁ48.30 | 0.08 | -111.30 to 23.80 | -ÂŁ12.50 | 0.76 | -91.70 to 66.60 | ÂŁ37.60 | 0.29 | -33.40 to 108.60 |
W2 | -ÂŁ43.40 | 0.16 | -122.50 to 48.40 | ÂŁ23.00 | 0.62 | -66.70 to 112.70 | -ÂŁ62.60 | 0.19 | -156.20 to 30.90 |
W3 | -ÂŁ37.60 | 0.17 | -116.80 to 37.40 | -ÂŁ66.60 | 0.10 | -146.20 to 12.09 | -ÂŁ62.90 | 0.10 | -138.60 to 12.60 |
W4 | -ÂŁ44.30 | 0.08 | -107.10 to 17.60 | -ÂŁ7.98 | 0.85 | -89.10 to 73.20 | -ÂŁ58.60 | 0.33 | -176.00 to 58.90 |
W5 | ÂŁ26.20 | 0.76 | -45.80 to 98.70 | ÂŁ32.70 | 0.34 | -34.90 to 100.40 | -ÂŁ48.60 | 0.22 | -125.90 to 28.60 |
Drug cost (ÂŁ) | |||||||||
W1 | -ÂŁ2.46 | 0.31 | -12.30 to 6.90 | -ÂŁ9.99 | 0.08 | -21.01 to 1.10 | -ÂŁ10.60 | 0.06 | -21.80 to 0.54 |
W2 | -ÂŁ16.90 | 0.06 | -26.50 to -8.20 | -ÂŁ3.90 | 0.32 | -11.70 to 3.80 | -ÂŁ5.90 | 0.20 | -15.00 to 3.10 |
W3 | -ÂŁ6.90 | 0.33 | -15.40 to 1.40 | -ÂŁ6.10 | 0.13 | -14.10 to 1.80 | ÂŁ8.50 | 0.15 | -19.90 to 2.90 |
W4 | -ÂŁ2.05 | 0.33 | -10.50 to 7.60 | -ÂŁ5.00 | 0.24 | -13.40 to 3.30 | -ÂŁ10.80 | 0.04 | -2110 to -0.50 |
W5 | -ÂŁ2.23 | Â | -11.80 to 8.10 | -ÂŁ2.50 | 0.54 | -10.0 to 5.50 | -ÂŁ6.40 | 0.40 | -21.40 to 8.50 |
Total NHS cost (ÂŁ) | |||||||||
W1 | -ÂŁ57.50 | 0.06 | -128.20 to 19.80 | -ÂŁ17.20 | 0.69 | -101.60 to 67.30 | ÂŁ20.60 | 0.59 | -54.70 to 95.80 |
W2 | -ÂŁ54.90 | 0.12 | -137.30 to 5.90 | ÂŁ15.50 | 0.74 | -77.00 to 108.00 | -ÂŁ66.00 | 0.19 | -166.60 to 34.60 |
W3 | -ÂŁ41.10 | 0.16 | -123.90 to 37.90 | -ÂŁ86.90 | 0.04 | -169.80 to -4.10 | -ÂŁ80.10 | 0.06 | -162.50 to 0.30 |
W4 | -ÂŁ65.60 | 0.03 | -135.08 to -3.10 | -ÂŁ21.20 | 0.62 | -105.60 to 63.30 | -ÂŁ64.00 | 0.30 | -186.30 to 8.30 |
W5 | ÂŁ16.70 | 0.66 | 62.10 to 93.70 | ÂŁ27.20 | 0.45 | -43.80 to 98.00 | -ÂŁ91.40 | 0.06 | -187.30 to 4.50 |