Cost-effectiveness of a universal strategy of brief dietary intervention for primary prevention in primary care: population-based cohort study and Markov model

Table 2 Health outcomes and cost-effectiveness of a healthy eating intervention in a population of 262,704 healthy participants

	Difference	Probability
	(Intervention-standard care)	(%)
Number entering intervention	262,704
Life years lived without disease (per 1,000)^a	41.9 (-17.4 to 101.0)	88.0
New incidences per 1,000 of:
Diabetes mellitus	-0.5 (-2.2 to 1.23)	67.7
Coronary heart disease	-0.6 (-2.4 to 1.3)	69.0
Stroke	0.02 (-1.5 to 1.6)	49.7
Colorectal cancer	0.04 (-0.7 to 0.8)	46.2
Life years lived with physical morbidity (per 1,000)^a
Single condition	-28.4 (-75.8 to 18.7)	84.6
Dual conditions	-7.2 (-28.9 to 14.4)	71.0
Triple conditions	-0.7 (-7.5 to 6.1)	56.1
Quadruple conditions	-0.0 (-1.4 to 1.5)	52.2
Life years lived with depression (per 1,000)^a	-2.9 (-16.6 to 11.2)	63.9
Total life years (per 1,000)^a	5.7 (-36.6 to 47.3)	41.1
Total intervention costs (£ per 1,000)	153,521 (153,462 to 153,583)	100.0
Incremental costs of non-intervention health care utilisation (£ per 1,000)	-13,765 (-93,093 to 66,556)	38.8
Incremental total costs (£ per 1,000)^a,b	139,755 (60,466 to 220,059)	99.8
Incremental QALYs (discounted 3.5%) (per 1,000)	4.3 (-8.8 to 18.0)	68.8
Incremental QALYs (discounted 1.5%) (per 1,000)	6.3 (-15.6 to 28.4)	67.0
Net health benefits (QALYs per 1,000)^b,c	-0.32 (-13.8 to 13.5)	47.9
Probability cost effective	47.9
At £30,000 per QALY (%)

^aper 1,000 healthy participants entering model; ^bdiscounted at 3.5%; ^cnet health benefit at a threshold of £30,000 per QALY.
Figures represent mean and 95% range of 2,000 simulations.

ISSN: 1478-7547